Oligosynthesis Columns

Prime Synthesis offers a wide variety of oligosynthesis columns in standard, or custom scales and chemistries. We also offer a precision column filling service using customer-supplied columns and/or solid supports. Please contact us for a price quotation based on your requirements.
 

Pipette Tip Style Columns

 
Prime Synthesis has worked with Integrated DNA Technologies to develop a high quality column that can be used with today’s most popular high-through-put synthesizers including:
 
ABI 3900TM, MermadeTM  Dr. OligoTM  and OligoMaker ApS
 
These columns use high purity nucleosides that are attached to CPG with a proprietary long chain alkyl amine linker (LCAA) licensed by Alnylam Pharmaceuticals. Each batch of nucleoside CPG undergoes extensive synthesis testing. The patented, high precision design has been licensed from McLuen Design, Inc. and is manufactured to the highest standards. Manufactured under GMP quality guidelines, their high quality and performance sets them apart from inferior knock-off competitors.
 
 

Luer Fitting Columns

Retro Columns

 
These cost-effective columns were designed and manufactured at Integrated DNA Technologies to perform with most standard “Vintage” synthesizers such as the ABI Model 394, and BioSearch Expedite. They are available in scales of 50 nmole, 200 nmole and 1 umole with 1000 Angstrom porosity CPG supports including: dA(bz), dC(Bz), dG(iBu) and dT.  Retro columns are only available in these standard formats.
 

Milligen/Biosearch Columns

A high-precision reproduction of the original design used on Models such as Cyclone and Expedite synthesizers. Their crimp design allows easy removal of the CPG for post-synthesis work-up outside of the column. They are available in scales of 50 nmole, 200 nmole and 1 umole. Larger scales are available by request. They are available with either 500 Angstrom or 1000 Angstrom porosity CPG supports in a wide variety of standard and custom chemistries.

ABI Style Crimp Columns

A high-precision reproduction of the original design used on Models such as the 394 series synthesizers. Their crimp design allows easy removal of the CPG for post-synthesis work-up outside of the column. They are available in scales of 50 nmole, 200 nmole and 1 umole. Larger scales are available by request. They are available with either 500 Angstrom or 1000 Angstrom porosity CPG supports in a wide variety of standard and custom chemistries.

ABI Style Snap Columns

A high-precision reproduction of the original design used on Models such as the 394 series synthesizers. Their snap design allows easy removal of the CPG for post-synthesis work-up outside of the column. They are available in scales of 50 nmole, 200 nmole and 1 umole. Larger scales are available by request. They are available with either 500 Angstrom or 1000 Angstrom porosity CPG supports in a wide variety of standard and custom chemistries.

Pharmacia Style Columns

A high-precision reproduction of the original design used vintage Pharmacia synthesizers. They are available in scales of 50 nmole, 200 nmole and 1 umole. Larger scales are available by request. They are available with either 500 Angstrom or 1000 Angstrom porosity CPG supports in a wide variety of standard and custom chemistries.