About Prime Synthesis

ABOUT PRIME SYNTHESIS

Prime Synthesis, Inc. was founded in the late 80’s to help meet the challenges of an explosive new area of molecular biology- genomics. The growth projections for the number of oligonucleotides needed to support this emerging science seemed astronomical at the time, but have since been far exceeded.

We are proud to have supplied DNA synthesis materials to most of the leading research labs over the years, and have followed this exciting market towards the final goals of genomically based diagnostics and therapeutics. Our research efforts have been focused on products that improve the efficiency both oligo research and production. Our market related growth has enabled us to achieve the economies of scale needed to lower our costs and yours.

A sharper focus

As the needs for the DNA synthesis market continues to change, we look forward to changing as well. Our latest efforts have been to develop refined chemistry and scale-up our custom solid supports for the therapeutic oligo market. However, we also wanted to leverage what we have learned about high efficiency oligo synthesis and make it available to the general oligo research market. To this end, we have formed a new division called 3-Prime, whose mission is to provide the highest quality synthesis solid supports, columns and other supplies to today’s oligonucleotide synthesis market.

Prime Synthesis, Inc. is located in Aston, PA, just outside of Philadelphia. Our 20,000 square foot facility houses our research laboratories, production areas and administrative offices. We have recently completed the construction of a 10,000 square foot GMP compliant production area with a suite of organic synthesis work areas, controlled porosity glass processing areas and a state-of-the-art quality control laboratory. Through collaborations with our local universities, we have access to an extensive array of the most advanced microscopy and spectroscopy instrumentation, as well as an impressive network of chemistry, materials science and biomedical consultants.